Solpadeine Express 24 tabs soluble

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For oral use.
Do not exceed the recommended dose!
Use the lowest dose necessary to achieve the effect for the shortest possible time! The minimum interval between doses of Solpadeine Express should be at least 4 hours. Adults (including the elderly) and children over 12 years of age: 1-2 tablets dissolved in half a glass of water every 4-6 hours as needed, but no more than 4 times a day. The maximum daily dose is 8 tablets. The maximum duration of continuous use without consulting a doctor: 5 days as a pain reliever and 3 days as an antipyretic.
If the recommended dose of the drug is exceeded, seek medical help immediately, even if you feel well.
An overdose of paracetamol can cause liver failure.
Special patient groups
Patients with impaired renal function: Before using Solpadeine Express, patients with impaired renal function should first consult a doctor. Restrictions associated with the use of drugs containing a combination of caffeine and paracetamol in patients with impaired renal function are mainly related to the paracetamol content of the drug.
Patients with impaired liver function: Before using Solpadeine Express, patients with impaired liver function should first consult a doctor. Restrictions associated with the use of drugs containing a combination of caffeine and paracetamol in patients with impaired liver function are mainly related to the paracetamol content of the drug.

Contraindications
• Hypersensitivity to paracetamol, caffeine or any other component of the drug;
• Severe liver and kidney dysfunction;
• Arterial hypertension;
• Glaucoma, sleep disorders;
• Children under 12 years of age;
• Pregnancy and breastfeeding;
• Epilepsy;
• Sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption, since the drug contains sorbitol.
• Concomitant use with other drugs containing paracetamol, lithium, as well as with caffeine-containing drinks.
With caution:
• Benign hyperbilirubinemia (including Gilbert's syndrome).
• Viral hepatitis.
• Alcoholic liver disease.
• Chronic alcoholism.
• Glucose-6-phosphate dehydrogenase deficiency.
• Mild to moderate liver and kidney dysfunction;
• Presence of severe infections, as taking the drug may increase the risk of metabolic acidosis,
• Use in patients with glutathione deficiency (particularly in extremely malnourished patients suffering from anorexia, or patients with a low body mass index).