Cardiomagnil 30 tab

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How to take, course of administration and dosage

1 tablet of Cardiomagnyl-Forte or 2 tablets of Cardiomagnyl (150 g ASA) on the first day of treatment, then 75 mg (1 tablet of Cardiomagnyl) 1 time per day. Take the tablet with a small amount of water.

If necessary, the tablets are chewed or crushed. It is recommended to consume after meals. The duration of treatment is determined by the doctor individually depending on the clinic, indications and severity of the disease.

Overdose

If signs of overdose are detected, the patient is hospitalized, the stomach is washed, sorption enteral drugs are prescribed, and, if necessary, alkaline diuresis is provided.

In the future, symptomatic therapy is necessary. In case of an overdose of cardiomagnyl, tachypnea develops, bleeding time is prolonged, nausea, anxiety, tinnitus, sweating, and decreased hearing acuity occur. Vomit contains streaks of blood. A dangerous dosage is considered to be 150 mg/kg.

In severe cases, ketoacidosis, cardiac arrhythmias, hypoglycemia, acute cardiovascular failure, hyperventilation, acute respiratory failure, and coma develop.

Special instructions

Prescribe with caution for gout and hyperuricemia (reduces the excretion of uric acid).

When taking glucocorticoids, it is possible to reduce the level of salicylates in the blood plasma; after discontinuation of glucocorticoids, salicylates increase (risk of overdose). While taking Cardiomagnyl, monitoring of a clinical blood test is necessary. Do not use before surgical interventions and in the postoperative period (risk of bleeding).

Patients with diabetes mellitus who take cardiomagnyl for a long time require correction of hypoglycemic agents (ASA causes hypoglycemia). Do not use in combination with ibuprofen (neutralizing the therapeutic effect of ASA).

Contraindications

• Kidney failure;
• taking methotrexate at a dose of more than 15 mg/week;
• age up to 18 years.
- a tendency to bleeding or a recent episode of bleeding (hemorrhagic diathesis, hemorrhagic stroke, hypothrombinemia, gastrointestinal bleeding, hemophilia);
• bronchial asthma in response to the administration of ASA;
• allergy to the components of the drug (especially ASA);
• deficiency of glucose-6-phosphate dehydrogenase;
Side effects

Hemorrhagic stroke, bleeding from the gastrointestinal tract, allergic reactions, bronchospasm.

Heartburn, dyspeptic disorders, irritable bowel syndrome, ulcers of the gastrointestinal mucosa, and perforation of an existing gastrointestinal ulcer may occur. A clinical blood test reveals eosinophilia, decreased platelet count, aplastic anemia, neutropenia, and agranulocytosis.

The coagulogram shows hypoprothrombinemia. Rarely, headache, tinnitus, drowsiness, and dizziness are observed.

Interaction

Antacids and cholestyramine reduce the absorption of the drug.

With simultaneous use, ASA enhances the effect of the following drugs: methotrexate - by reducing renal clearance and displacing it from protein binding; heparin and indirect anticoagulants - due to disruption of platelet function and displacement of indirect anticoagulants from binding with proteins; thrombolytic and antiplatelet drugs (ticlopidine); digoxin - due to a decrease in its renal excretion; hypoglycemic agents (insulin and sulfonylurea derivatives) - due to the hypoglycemic properties of ASA itself in high doses and displacing sulfonylurea derivatives from binding with proteins; valproic acid - by displacing it from its connection with proteins. An additive effect is observed when taking ASA simultaneously with ethanol (alcohol).

ASA weakens the effect of uricosuric drugs (benzbromarone) due to competitive tubular elimination of uric acid. By enhancing the elimination of salicylates, systemic corticosteroids weaken their effect.

The health is harmed by improper usage! Please carefully read the information in the package booklet or on the packaging!

Discuss the use of this medication with your doctor or pharmacist.

Never use the medication for longer than recommended.

Patients with hypersensitivity to the components of the medication should NOT use the medication.

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