Solpadeine Express 12 tabs soluble

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The lowest dose necessary to achieve the desired effect should be used for the shortest possible period of time! The minimum interval between doses of Solpadeine Express should be at least 4 hours. Adults (including the elderly) and children over 12 years of age: 1-2 tablets dissolved in half a glass of water every 4-6 hours as needed, but no more than 4 times per day. The maximum daily dose is 8 tablets. The maximum duration of continuous use without consulting a doctor is 5 days for pain relief and 3 days for fever reduction.
If the recommended dose is exceeded, seek medical attention immediately, even if you feel well.

Contraindications
• Hypersensitivity to paracetamol, caffeine or any other component of the drug;
• Severe liver and kidney dysfunction;
• Arterial hypertension;
• Glaucoma, sleep disorders;
• Children under 12 years of age;
• Pregnancy and breastfeeding;
• Epilepsy;
• Sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption, since the drug contains sorbitol.
• Concomitant use with other drugs containing paracetamol, lithium, as well as with caffeine-containing drinks.
With caution:
• Benign hyperbilirubinemia (including Gilbert's syndrome).
• Viral hepatitis.
• Alcoholic liver disease.
• Chronic alcoholism.
• Glucose-6-phosphate dehydrogenase deficiency.
• Mild to moderate liver and kidney dysfunction;
• Presence of severe infections, as taking the drug may increase the risk of metabolic acidosis,
• Use in patients with glutathione deficiency (particularly in extremely malnourished patients suffering from anorexia, or patients with a low body mass index).