Solpadeine express 12 tab. soluble

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For oral administration.
Do not exceed the indicated dose!
The smallest dose required to achieve the effect should be used for the shortest possible period of time! The minimum interval between doses of Solpadeine Express should be at least 4 hours. Adults (including the elderly) and children over 12 years of age: 1-2 tablets dissolved in half a glass of water every 4-6 hours, as needed, but no more 4 times a day. The maximum daily dose is 8 tablets. Maximum duration of continuous use without consulting a doctor: 5 days as an analgesic and 3 days as an antipyretic.
If you exceed the recommended dose of the drug, seek medical help immediately, even if you feel well.
An overdose of paracetamol can cause liver failure.
Special patient groups
Patients with impaired renal function: Before using the drug Solpadeine Express, patients with impaired renal function should first consult a doctor. Restrictions associated with the use of drugs containing a combination of caffeine and paracetamol in patients with impaired renal function are mainly associated with the paracetamol content of the drug.
Patients with impaired liver function: Before using the drug Solpadeine Express, patients with impaired liver function should first consult a doctor. Restrictions associated with the use of drugs containing a combination of caffeine and paracetamol in patients with impaired liver function are mainly related to the paracetamol content of the drug.

• Hypersensitivity to paracetamol, caffeine or any other component of the drug;
• Severe liver and kidney dysfunction;
• Arterial hypertension;
• Glaucoma, sleep disorders;
• Children under 12 years of age;
• Pregnancy and breastfeeding;
• Epilepsy;
• Sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption, because. the drug contains sorbitol.
• Simultaneous use with other medications containing paracetamol, lithium, as well as caffeine-containing drinks.
Carefully:
• Benign hyperbilirubinemia (including Gilbert's syndrome).
• Viral hepatitis.
• Alcoholic liver disease.
• Chronic alcoholism.
• Glucose-6-phosphate dehydrogenase deficiency.
• Impaired liver and kidney function of mild to moderate severity;
• Presence of severe infections, because taking the drug may increase the risk of metabolic acidosis,
• Use in patients with glutathione deficiency (in particular, extremely malnourished patients suffering from anorexia or patients with a low body mass index).
If you have any of the listed diseases/conditions/risk factors, you should consult your doctor before taking the product.
Pregnancy and lactation:
Pregnancy
The use of the drug during pregnancy is not recommended!
Paracetamol
The lowest dose needed to achieve effect should be taken for the shortest possible period of time.
Caffeine
The use of caffeine may increase the risk of spontaneous abortion, so its use is not recommended during pregnancy.
Breastfeeding period
The use of the drug during breastfeeding is not recommended!
Paracetamol
Paracetamol is excreted in breast milk, but in clinically insignificant quantities when used in recommended doses.
Caffeine
Caffeine passes into breast milk and may have a stimulating effect on the breastfed infant, but no significant toxicity has been reported.
If no improvement is observed while taking the drug, or the headache becomes constant, you should consult a doctor.
The drug Solpadein Fast should not be used with other paracetamol-containing drugs, since taking the drugs together can cause an overdose of paracetamol.
An overdose of paracetamol may cause liver failure, which may lead to the need for liver transplantation or death.
The drug Solpadeine Fast should not be taken with caffeine-containing foods (tea, coffee, etc.), because this can lead to restlessness, anxiety, irritability, insomnia, headache, gastrointestinal disorders, tachycardia, cardiac arrhythmia.
Patients with glutathione deficiency due to an eating disorder, cystic fibrosis, HIV infection, fasting, malnutrition are susceptible to overdose, so precautions must be taken and it is recommended to consult a doctor before taking the drug.
Cases of liver failure/impaired liver function have been reported with a small overdose of paracetamol (5 g or more) in patients with low glutathione levels, in particular in extremely malnourished patients suffering from anorexia, chronic alcoholism or patients with a low body mass index.
The use of Solpadeine Fast by patients with low glutathione levels, for example, with sepsis, may increase the risk of developing metabolic acidosis, accompanied by symptoms of rapid, difficult breathing (feeling of shortness of breath, shortness of breath), nausea, vomiting, loss of appetite. If these symptoms occur simultaneously, you should immediately consult a doctor.
To avoid toxic liver damage, paracetamol should not be combined with alcoholic beverages, or taken by persons prone to chronic alcohol consumption.
Concomitant liver diseases increase the risk of further liver damage when taking Solpadeine Fast. When taking the drug in patients with non-alcoholic cirrhosis of the liver, there is a high risk of overdose.
Patients suffering from atopic bronchial asthma and hay fever have an increased risk of developing allergic reactions.
When conducting tests to determine uric acid and blood glucose levels, you should inform your doctor about taking the product.
The product can change the results of doping control tests for athletes.
For patients on a salt-free or low-salt diet, the sodium content of the tablet (427 mg) should be taken into account when calculating daily salt intake.
The product contains sorbitol. Patients with fructose intolerance should not use this drug.
Impact on the ability to drive vehicles and machinery:
The effect of the product on the ability to drive a car and operate machinery is unlikely.