Rectally.
1 sup. contains human recombinant interferon alpha-2b as an active substance in the indicated dosages (150,000 IU, 500,000 IU, 1,000,000 IU, 3,000,000 IU).
ARVI (including influenza), incl. complicated by bacterial infection in children and adults - in complex therapy. The recommended dose for adults, including pregnant women and children over 7 years of age, is VIFERON® 500,000 IU, 1 supp. 2 times a day after 12 hours every day for 5 days.
Children under 7 years old, incl. for newborns and premature infants with a gestational age of more than 34 weeks, the use of the drug VIFERON® 150,000 IU, 1 supp. 2 times a day after 12 hours every day for 5 days.
Premature newborns with a gestational age of less than 34 weeks are recommended to use the drug VIFERON® 150,000 IU, 1 supp. 3 times a day after 8 hours every day for 5 days.
Children with an increased risk of complications and long-term course of the disease (see “Special Instructions”) aged 1 month to 3 years - 1 supp. 500,000 IU 2 times a day (every 12 hours) daily for 5 days, then 1 supp. 150,000 IU 2 times a day (every 12 hours) daily for the next 5 days. Children from 3 to 7 years old - 1 sup. 500,000 IU 2 times a day (every 12 hours) daily for 5 days, then in the morning 1 sup. 500,000 IU and after 12 hours 1 supp. 150,000 IU daily for the next 5 days. Children from 7 years to 18 years old - 1 sup. in the morning. 1,000,000 IU, then after 12 hours 1 supp. 500,000 IU daily for 5 days, then 1 supp. 500,000 IU 2 times a day (every 12 hours) daily for the next 5 days.
Infectious and inflammatory diseases of newborns, incl. premature babies: pneumonia (bacterial, viral, chlamydial), meningitis (bacterial, viral), sepsis, intrauterine infection (chlamydia, herpes, CMV infection, enterovirus infection, candidiasis, including visceral, mycoplasmosis) - in complex therapy. Recommended dose for newborns, incl. premature babies with a gestational age of more than 34 weeks - the drug VIFERON® 150,000 IU daily, 1 supp. 2 times a day after 12 hours. The course of treatment is 5 days.
Premature newborns with a gestational age of less than 34 weeks are recommended to use the drug VIFERON® 150,000 IU daily, 1 supp. 3 times a day after 8 hours. The course of treatment is 5 days.
Recommended number of courses for various infectious and inflammatory diseases: sepsis - 2-3 courses, pneumonia, meningitis - 1-2 courses, herpes infection - 2 courses, enterovirus infection - 1-2 courses, CMV infection - 2-3 courses, mycoplasmosis , candidiasis, incl. visceral, 2–3 courses. The break between courses is 5 days. According to clinical indications, therapy can be continued.
Chronic viral hepatitis B, C, D in children and adults - in complex therapy, incl. in combination with the use of plasmapheresis and hemosorption for chronic viral hepatitis of pronounced activity, complicated by cirrhosis of the liver. The recommended dose for adults is the drug VIFERON® 3,000,000 IU, 1 supp. 2 times a day after 12 hours every day for 10 days, then 3 times a week every other day for 6–12 months. The duration of treatment is determined by clinical effectiveness and laboratory parameters.
For children under 6 months, 300,000–500,000 IU/day is recommended; from 6 to 12 months - 500,000 IU/day.
For children from 1 to 7 years old, 3,000,000 IU/m2/day is recommended; over 7 years - 5,000,000 IU/m2/day.
The drug is used 2 times a day every 12 hours for the first 10 days, then 3 times a week every other day for 6–12 months. The duration of treatment is determined by clinical effectiveness and laboratory parameters.
The daily dose of the drug for each patient is calculated by multiplying the recommended dose for a given age by the body surface area calculated using the nomogram for calculating body surface area by height and weight according to Garford, Terry and Rourke. The calculation of a single dose is carried out by dividing the calculated daily dose into 2 administrations, the resulting value is rounded up to the dosage of the suppository.
In case of chronic viral hepatitis of pronounced activity and cirrhosis of the liver, before performing plasmapheresis and/or hemosorption, it is recommended to use the drug VIFERON® 150,000 IU in children under 7 years of age, and for children over 7 years old - the drug VIFERON® 500,000 IU, 1 supp. 2 times a day after 12 hours every day for 14 days.
Infectious and inflammatory diseases of the urogenital tract (chlamydia, CMV infection, ureaplasmosis, trichomoniasis, gardnerellosis, papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis) in adults, including pregnant women - in complex therapy. The recommended dose for adults is VIFERON® 500,000 IU, 1 supp. 2 times a day after 12 hours every day for 5–10 days. According to clinical indications, therapy can be continued.
Pregnant women from the second trimester of pregnancy (starting from the 14th week of gestation) are recommended to use the drug VIFERON® 500,000 IU, 1 supp. 2 times a day after 12 hours every day for 10 days, then for 9 days
